rtPA (actilyse) (recombinant tissue plasminogen activator) (50mg/vial)
STEMI:
>67kg (2支): 15mg ivd 1-2min
50mg ivd 30min
35mg ivd 60min
<=67kg 15mg ivd 1-2min
0.75mg/kg (50kg=37.5mg)
0.5mg/kg (50kg=25mg)
急性中風
> 100kg (total 90mg)
10% (9mg) ivd 1min; 90% (81mg) ivd 60min
<= 100kg (0.9mg/ kg) (10% ivd 1min, 90% ivd 60min)
50kg= 5mg/ 45mg
60kg= 6mg/ 54mg
70kg= 7mg/ 63mg
80kg= 8mg/ 72mg
Heparin (25000u/vial)
20000u in N/S 500ml, 50kg run 15ml/h; 60kg (18ml/h); 70kg (21ml/h)
LMWH
Fragmin (5000 IU/amp): 2500IU sc q12
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