2013年9月12日 星期四

Hyperthyroidism

病因: (Lancet 2003;362:459)

  -Graves' dz (60-80% of thyrotoxicosis)
  -thyroiditis (thyrotoxic phase of)
       -subacute (granulomatous) thyroiditis
       -painless (lymphocytic) thyroidits
  -toxic adenoma (SNG or MNG)
  -central hyperthyroidism (TSH-secreting pituitaty tumor) or pituitary resistance to thyroid hormone
  -其他:
       藥物: amiodarone, 碘引起,
       自行服用eltroxin (thyrotoxicosis factitia)
       struma ovarii (3% of pvarian dermoid tumors & teratoma)
       hCG-secreting tumor (choriocarcinoma)
       large deposits of metastatic FTC (follicular thyroid cancer)



Graves' dz (NEJM 2008;358:2594)

流病:
    -女(5-10x); most 40-60y at Dx

甲狀腺抗體(+):
   -TBII or TSI (TSH R Ab) ((+) in 80% pt)
   -anti-TPO (microsomal Ab), anti-thyroglobulin
   -ANA

臨床:

  -Hyperthyroidism 表現:
       tremor (restlessness,


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