病因: (Lancet 2003;362:459)
-Graves' dz (60-80% of thyrotoxicosis)
-thyroiditis (thyrotoxic phase of)
-subacute (granulomatous) thyroiditis
-painless (lymphocytic) thyroidits
-toxic adenoma (SNG or MNG)
-central hyperthyroidism (TSH-secreting pituitaty tumor) or pituitary resistance to thyroid hormone
-其他:
藥物: amiodarone, 碘引起,
自行服用eltroxin (thyrotoxicosis factitia)
struma ovarii (3% of pvarian dermoid tumors & teratoma)
hCG-secreting tumor (choriocarcinoma)
large deposits of metastatic FTC (follicular thyroid cancer)
Graves' dz (NEJM 2008;358:2594)
流病:
-女(5-10x); most 40-60y at Dx
甲狀腺抗體(+):
-TBII or TSI (TSH R Ab) ((+) in 80% pt)
-anti-TPO (microsomal Ab), anti-thyroglobulin
-ANA
臨床:
-Hyperthyroidism 表現:
tremor (restlessness,
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